MB 20 series

The Alfa Laval MB 20 series is designed for cell-harvesting centrifugation in pilot-scale research and small-scale manufacturing. MB 20 separators are specifically developed for gentle and highly efficient harvesting of biopharma and biotech fermentations, producing end products such as rDNA, vaccines, and probiotics. In addition, the MB 20 Bactofuge™ provides continuous solids removal, making it particularly suitable for high-concentration cultures.

cell harvesting centrifugation pilot scale

Separator system for cell harvesting centrifugation, optimized for biopharma and biotech applications

  • Efficient and gentle separation resulting in high yield
  • Low lysis and high filterability, reducing costs of downstream filtration
  • Enables continuous removal of solids up to 40% concentration in feed
  • Accurate scalability from pilot scale to large-scale production
  • Fully automated and flexible for process variations

The complex and delicate nature of cells requires careful handling to secure high yields and facilitate downstream filtering. Through continuous and highly efficient separation, MB 20 and MB 20 Bactofuge centrifuges bring improved productivity to biopharma applications at pilot scale.

The MB range of centrifuges incorporates unique Alfa Laval technologies, like Hermetic Design™ for enhanced product handling in various separation applications, and Bactofuge®, facilitating gentle but speedy processing of high-solids broths with continuous discharge of a highly concentrated solids phase. With these innovations, the MB centrifuges add profitability and offers unmatched scalability for biotech and biopharmaceutical pilot projects and small-scale production.

 

Innovative technology behind MB 20 series

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Hermetic Design™

Alfa Laval Hermetic Design™ improves product handling in a wide range of separation applications. The air-tight and bottom-fed bowl enables gentle acceleration of media, with minimal foaming and oxygen pick-up, providing high product yield and low filter costs.

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Bactofuge®

Alfa Laval Bactofuge® enables gentle and speedy continuous solids removal for high concentrations cultures, resulting in higher yield, with minimum risk of clogging.​ In addition to higher separation output, Bactofuge preserves the quality of the solids stream, and allows a flexible and controlled operation. 

The MB 20 range of centrifuges for cell harvesting

Premium separation performance in a plug & play system. Fully automated and user-friendly operation for small-scale biopharma and biotech processing, with the option of Bactofuge® - providing continuous solids phase removal.

MB 20

  • 2-phase clarification
  • 50 - 600 l/h processing capacity

 

MB 20 Bactofuge

  • 3-phase separation
  • 50 - 600 l/h processing capacity
  • Bactofuge®: continuous solids removal for high concentrations cultures
  • With the optional conversion kit, you get 2-1 centrifuges, converting 3-phase to 2-phase clarification

Find out how the MB 20 series work

Do you want to learn more about MB 20? Watch our short animation and discover more.

Schaalbaarheid voor celcentrifuge

Scalable performance

No matter your application, you can trust the Alfa Laval MB 20 series centrifuges to perform reliably. Whether you're doing pilot testing or small-scale production, these centrifuges use the same innovative technologies as the bigger Alfa Laval separators. This means that the results from the MB 20 separators can easily match up with both the Alfa Laval Culturefuge range and the Alfa Laval MB separator range.

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Separation expertise for next-generation food

The world`s growing population deserves nutritious and tasty food, produced without harming our planet. The food landscape is changing, through groundbreaking research and cutting-edge technology. Alfa Laval provides unmatched separation expertise for this transformation: bringing scalability, profitability, and resource efficiency to next-generation food processes, like cellular agriculture.

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El innovador en separadores

¿Desea obtener más información sobre nuestras innovaciones en tecnología de separación? Haga clic en el enlace siguiente. Alfa Laval inventó el primer separador de discos apilados y ha liderado el desarrollo de la tecnología de centrifugación durante más de un siglo. Nos complace compartir con usted la experiencia que hemos adquirido a lo largo de este tiempo. Visite nuestra base de conocimientos Separator Innovator para obtener más información sobre los avances en separación y las medidas que Alfa Laval está tomando para seguir revolucionando la tecnología.

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